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Allele : Hspa1b<tm1Msk> heat shock protein 1B; targeted mutation 1, Demetrius Moskophidis

Primary Identifier	MGI:2183891	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Hspa1b
Transmission	Germline	Strain of Origin	129S2/SvPas
Is Recombinase	false	Is Wild Type	false

molecularNote

Most of the coding region of the gene was replaced with an in frame lacZ floxed TK-neo cassette via homologous recombination. Southern blot and PCR genotype analysis confirmed the targeted allele in homozygous mutant animals.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
hsp70.1<->,
hsp70.1<->

earliestPublication:
Huang L, et al. (2001) Insights into Regulation and Function of the Major Stress-Induced hsp70 Molecular Chaperone In Vivo: Analysis of Mice with Targeted Gene Disruption of the hsp70.1 or hsp70.3 Gene. Mol Cell Biol 21(24):8575-91

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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