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Allele : Fgr<tm2Hev> FGR proto-oncogene, Src family tyrosine kinase; targeted mutation 2, Harold E Varmus

Primary Identifier  MGI:2384041 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fgr
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The insertion of a neomycin selection cassette replaced exon 4 and precluded the complete translation of proteins initiated from a potential start codon at position 59 in the 3' terminal of exon 2. Normal protein was undetected by Western blot analysis of homozygous mutant mice, however, the lack of truncated carboxy terminal peptides was not directly verified.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • fgr-delta4,
  • fgr-delta4
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele