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Publication : Genetic variation in mouse salivary amylase rate of synthesis.

First Author  Hjorth JP Year  1979
Journal  Biochem Genet Volume  17
Issue  7-8 Pages  665-82
PubMed ID  94264 Mgi Jnum  J:6289
Mgi Id  MGI:54766 Doi  10.1007/BF00502125
Citation  Hjorth JP (1979) Genetic variation in mouse salivary amylase rate of synthesis. Biochem Genet 17(7-8):665-82
abstractText  Heterozygotes from matings of the mouse strains YBR/Cv and C3H/As have about 3 times more YBR-amylase than C3H-amylase in the saliva. The determinant for this quantitative effect is located on linkage group XVI close to or with in the structural gene for salivary amylase. The quantitative effect is the result of an increase in the rate of synthesis of YBR-amylase, and the determinant is cis acting. Studies of other mouse strains suggest that regulatory genetic elements may modulate salivary amylase production.
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