| Primary Identifier | MGI:2183814 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(APOB)11Rub |
| Strain of Origin | FVB | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The human APOB gene (~19 kb of genomic sequence 5' to the translational start site of the gene and ~14kb of genomic sequence 3' to the transcription termination site) was introduced into fertilized FVB mouse embryos. Multiple lines were generated, ranging in copy number from 1 to 11 for the human gene, by Southern blot. This transgene is the high-expressing line, with an estimated eleven copies of the APOB gene in liver of these mice. |
