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Allele : Fgg<tm1Fjc> fibrinogen gamma chain; targeted mutation 1, Francis J Castellino

Primary Identifier  MGI:2384029 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fgg
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The entire coding region of the endogenous locus was replaced with a neomycin selection cassette. Western blot analysis of blood plasma showed the absence of the gamma polypeptide, preventing the formation of the fibrinogen heterodimer in homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Fib-,
  • Fib-,
  • FG<->,
  • FG<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

16 Publication categories

Trail: Allele