| Primary Identifier | MGI:2384155 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Smn1 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Animals heterozygous for the targeted mutation Smntm1Jme were mated to a cre recombinase transgenic line to delete the floxed exon 7. Deletion of exon 7 in mRNA from the resulting animals was confirmed by RT-PCR analysis. Heterozygous exon 7 deletion animals were intercrossed to generate homozygous mutants. Homozygous mutant embryos were detected by PCR genotype analysis at E9.5. |
