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Allele : Pafah1b1<tm2Awb> platelet-activating factor acetylhydrolase, isoform 1b, subunit 1; targeted mutation 2, Anthony Wynshaw-Boris

Primary Identifier  MGI:2384060 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Pafah1b1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed PGK-neo cassette was inserted into intron 2 and a third loxP site was introduced into intron 6 via homologous recombination. This allele is hypomorphic, because of disruption of transcription or splicing by the insertion of a phosphoglycerate kinase neomycin cassette from the targeting vector into the second intron (J:82268).
  • mutations:
  • Insertion
  • synonyms:
  • Pafah1b1<loxPex3-6>,
  • Pafah1b1-loxP,
  • Lis1-loxP,
  • Pafah1b1-loxP,
  • Pafah1b1<loxPex3-6>,
  • Lis1-loxP
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

27 Publication categories