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Allele : Syk<tm1Tyb> spleen tyrosine kinase; targeted mutation 1, Victor L J Tybulewicz

Primary Identifier  MGI:2384078 Allele Type  Targeted
Attribute String  Null/knockout Gene  Syk
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  The insertion of a neomycin selection cassette disrupted the exon encoding the subdomain I of the kinase domain. The absence of protein in mice homozygous for the allele was verified by Western blot analysis.
  • mutations:
  • Insertion
  • synonyms:
  • syk-,
  • syk-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

84 Publication categories