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Allele : Hif1a<tm1Rsjo> hypoxia inducible factor 1, alpha subunit; targeted mutation 1, Randall S Johnson
Primary Identifier  MGI:2385358 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hif1a
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence in exon 2 encoding the basic helix-loop-helix domain was replaced with a neomycin selection cassette. The absence of transcript and functional protein was shown by Northern blot analysis and an electromobility shift assay.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Hif1alpha<->,
  • HIF-1alpha<->,
  • Hif1alpha<->,
  • HIF-1alpha<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories

Trail: Allele




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