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Allele : Hif1a<tm2Rsjo> hypoxia inducible factor 1, alpha subunit; targeted mutation 2, Randall S Johnson

Primary Identifier  MGI:2385361 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Hif1a
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence encoding the basic helix-loop-helix domain was disrupted by the insertion of a construct containing lacZ followed by a floxed neo cassette via homologous recombination. The neo cassette was excised by the transient transfection of targeted ES cells by cre recombinase. Expression of lacZ was visualized via Xgal staining.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele