| Primary Identifier | MGI:2385585 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Tuba1-MAPT)14Vle |
| Strain of Origin | (C57BL/6 x SJL)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A murine Tuba1 promoter was adjoined to a minigene comprised of the complete coding region of the MAPT gene that included modified intronic sequence flanking exons 2 and 3 to drive expression of the downstream gene construct in the CNS. Western blot analysis showed the MAPT protein to be expressed at levels approximately 5.5 fold higher than the endogenous mouse counterpart. |
