Primary Identifier | MGI:2385787 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Slc26a4 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 8 was replaced with a neomycin selection cassette via homologous recombination. While, normal transcript was undetected by RT-PCR and Northern blot analyses of total kidney RNA isolated from homozygous mutant mice, RT-PCR revealed the presence of an aberrant transcript containing a portion of the neo cassette. |