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Allele : Minpp1<tm1Prr> multiple inositol polyphosphate histidine phosphatase 1; targeted mutation 1, Paul R Reynolds

Primary Identifier  MGI:2385788 Allele Type  Targeted
Attribute String  Null/knockout Gene  Minpp1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A 2 kb region of the gene including exon 1 and part of intron 1 was replaced with a neomycin resistance cassette via homologous recombination, resulting in deletion of the sequences encoding the active site. Northern blot analysis did not detect gene expression in homozygous mutants. Brain extracts from homozygous mutants contained no detectable enzymatic activity.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Minpp1<->,
  • Minpp1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele