Primary Identifier | MGI:2384622 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Men1 |
Transmission | Germline | Strain of Origin | 129T2/SvEms |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Floxed sequence including exon 2 and a neomycin cassette was excised from Men1tm1Gfk by the expression of cre recombinase. Exon 2 contained the initiator methionine and 400 bp of coding sequence. Western blot analysis showed an absence of encoded protein in homozygous mutant embryos. |