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Allele : Nrf1<tm1Rcs> nuclear respiratory factor 1; targeted mutation 1, Richard C Scarpulla

Primary Identifier  MGI:2385947 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Nrf1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence extending from within exon 2 to within exon 4 was replaced with a cassette containing the lacZ and neo genes. The deleted region encoded amino acids 86 through 166, which make up the nuclear localization signal and the DNA binding and dimerization domains. Expression of beta-galactosidase was determined to be driven by the endogenous promoter.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele