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Allele : Tg(APPSWE)2576Kha transgene insertion 2576, Karen Hsiao Ashe
Primary Identifier  MGI:2385631 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(APPSWE)2576Kha
Strain of Origin  (C57BL/6 x SJL)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Overexpression of the human APP gene encoding the APP695.SWE mutation (K670N and M671L). The construct contained the APP gene fused to the hamster prion protein promoter. APP expression was measured in brains of transgenic mice by quantitation of immunoblots.
  • mutations:
  • Insertion
  • synonyms:
  • APPswe Tg2576,
  • APPK670N,M671L,
  • hAPP,
  • TgN(APPSWE)2576,
  • Tg(APPSWE)2576Kahs,
  • APP695swe,
  • APPswe Tg2576,
  • Tg2576,
  • TgN(APPSWE)2576,
  • hAPP,
  • APP695swe,
  • APPSw,
  • Tg(HuAPP695.K670-M671L)2576,
  • Tg(APPSWE)2576Kahs,
  • APPSw,
  • K670N/M671L,
  • Tg(APPSWE)2576HKahs,
  • Tg(HuAPP695.K670-M671L)2576,
  • Tg2576,
  • K670N/M671L,
  • APPK670N,M671L,
  • Tg(APPSWE)2576HKahs
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

8 Carried By

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0 Driven By

739 Publication categories

Trail: Allele




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