Primary Identifier | MGI:2385916 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Tie1-cre)9Ref |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The transgene is composed of a 1.15 kb fragment of mouse Tie1 promoter fused to the cre recombinase gene and a nuclear localization signal, and a separate floxed PGK-neo cassette. The mouse Tie1 promoter directs expression of the cre transgene in endothelial cells. |