Primary Identifier | MGI:2386171 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Fli1)1Ber |
Strain of Origin | CD-1 | Is Recombinase | false |
Is Wild Type | false |
description | This mutation is representative of 3 transgenic founders designated as B6, B7, and B8 carrying 20, 8, and 4 copies of the transgene, respectively. |
molecularNote | The mouse H2-K1 promoter was used to express a 1.73 kb mouse Fli1 cDNA in a wide range of tissues. RNase protection assay confirmed transgene expression in mutant animals and Western blot analysis detected transgene expression in all tissues examined. Expression of endogenous Fli1 was also found to be elevated in transgenic animals. |