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Allele : Lyn<tm1Tya> LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1, Tadashi Yamamoto

Primary Identifier  MGI:2386196 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lyn
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 4, which encodes the amino terminal portion of the SH3 domain, was disrupted by the insertion of neomycin selection cassette. The absence of both isoforms was verified by Western blot analysis of spleen and cerebellum tissue obtained from homozygous mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • lyn<->,
  • lyn<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

26 Publication categories

Trail: Allele