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Allele : Nkx2-6<tm1Siz> NK2 homeobox 6; targeted mutation 1, Seigo Izumo

Primary Identifier  MGI:2386678 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nkx2-6
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by replacement of exon 2, which encodes the homeodomain and NK-2 specific domain, with a neomycin resistance cassette. Absence of gene expression in homozygous mutants was confirmed by in situ hybridization of E9.5 embryos using a probe to exons 1 and 2.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Nkx2.6<->,
  • Nkx2.6<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele