Primary Identifier | MGI:2386850 | Allele Type | Targeted |
Attribute String | Constitutively active, Inserted expressed sequence, Null/knockout | Gene | Mesp2 |
Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The coding sequences were replaced by an in-frame Notch1 intracellular cDNA sequence followed by a PGK-neomycin resistance cassette. This allele expresses an activated form of NOTCH1 under the control of the Mesp2 promoter. |