Primary Identifier | MGI:2386100 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Plcg2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 3.8 kb region of the gene containing exon 2 was replaced with a neomycin resistance gene via homologous recombination. Spleen extracts from homozygous mutant animals did not contain protein product as determined by immunoprecipitation and Western blot analysis using antibodies directed against the C-terminus of the protein. |