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Publication : Impaired Peyer's patch development in BOB.1/OBF.1-deficient mice.

First Author  Betzler AC Year  2021
Journal  Eur J Immunol Volume  51
Issue  7 Pages  1860-1863
PubMed ID  33733501 Mgi Jnum  J:339887
Mgi Id  MGI:6719427 Doi  10.1002/eji.202048578
Citation  Betzler AC, et al. (2021) Impaired Peyer's patch development in BOB.1/OBF.1-deficient mice. Eur J Immunol 51(7):1860-1863
abstractText  BOB.1/OBF.1 expression regulates the transcription of direct and indirect target genes. We propose that BOB.1/OBF.1 affects CXCL13-CXCR5 signaling of LTinducer and LTorganizer cells during embryonic Peyer's patch organogenesis as well as of B cells and follicular dendritic cells during lymphocyte homing at postnatal stages of secondary lymphoid organ development.
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