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Allele : Rara<tm3.1Ipc> retinoic acid receptor, alpha; targeted mutation 3.1, Pierre Chambon

Primary Identifier  MGI:2386107 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rara
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  The floxed fragment containing exon 8 was excised from Raratm3Ipc by mating with mice carrying Tg(CMV-cre)1Ipc . The deletion eliminated the majority of the DNA binding domain and introduced a frameshift mutation. A lack of protein expression was demonstrated in homozygous mutant mice via immunohistochemical analysis of testis sections.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • RARalpha L<->,
  • RARalpha L<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories

Trail: Allele