| Primary Identifier | MGI:2386117 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Igfbp2 |
| Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 3 and 0.6 kb of downstream intronic sequences containing the exon/intron boundary was replaced with a neomycin resistance gene via homologous recombination. Absence of mRNA and protein expression in homozygous mutant animals was confirmed by Northern blot analysis of brain and liver tissue using a cDNA probe to rat Igfbp2 and by Western blot analysis of serum proteins. |
