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Allele : Rasgrp1<tm1Jstn> RAS guanyl releasing protein 1; targeted mutation 1, James C Stone

Primary Identifier  MGI:2386261 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rasgrp1
Transmission  Germline Strain of Origin  129P3/J
Is Recombinase  false Is Wild Type  false
description  ES cell line = NX1.
molecularNote  Exon 2 was disrupted by the insertion of a cassette containing both Beta-galactosidase and neomycin resistance genes. While the translation of a fusion protein containing residues 1 through 16 of the endogenous joined to the Beta-galactosidase protein was expected, such a polypeptide was undetected by Western blot analysis of thymus and spleen extracts obtained from homozygous mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • RasGRP1<->,
  • RasGRP1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

44 Publication categories

Trail: Allele