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Allele : Vegfa<tm4Pec> vascular endothelial growth factor A; targeted mutation 4, Peter Carmeliet

Primary Identifier  MGI:2386595 Allele Type  Targeted
Gene  Vegfa Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Genomic sequence containing exons 4 through 8 was replaced with corresponding cDNA. The resultant allele lacks splice sites and thereby produces a single isoform with high receptor binding properties. The exclusive presence of this isoform was verified by quatitative RT-PCR.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • VEGF<188>,
  • VEGF<188>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

13 Publication categories

Trail: Allele