Primary Identifier | MGI:2386760 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Esr1 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The mutation is a derivative of Esr1tm1Mma. The floxed exon 3 and TK-neo cassette were deleted by mating Esr1tm1 animals to a cre-expressing line. Absence of gene expression was confirmed by Western blot and RT-PCR analysis of uterus protein and RNA from homozygous mutant animals. |