| Primary Identifier | MGI:2386761 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Esr2 |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by insertion of a neomycin resistance cassette into exon 3 encoding the first zinc finger domain via homologous recombination. RT-PCR analysis of ovary mRNA from mutant animals detected 3 faint RNA species all lacking exon 3. Immunohistochemical analysis of ovary sections from homozygous mutant animals did not detect protein product. |
