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Publication : Simultaneous optical and electrical in vivo analysis of the enteric nervous system.

First Author  Rakhilin N Year  2016
Journal  Nat Commun Volume  7
Pages  11800 PubMed ID  27270085
Mgi Jnum  J:239904 Mgi Id  MGI:5882008
Doi  10.1038/ncomms11800 Citation  Rakhilin N, et al. (2016) Simultaneous optical and electrical in vivo analysis of the enteric nervous system. Nat Commun 7:11800
abstractText  The enteric nervous system (ENS) is a major division of the nervous system and vital to the gastrointestinal (GI) tract and its communication with the rest of the body. Unlike the brain and spinal cord, relatively little is known about the ENS in part because of the inability to directly monitor its activity in live animals. Here, we integrate a transparent graphene sensor with a customized abdominal window for simultaneous optical and electrical recording of the ENS in vivo. The implanted device captures ENS responses to neurotransmitters, drugs and optogenetic manipulation in real time.
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