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Allele : Vav1<tm2Bbd> vav 1 oncogene; targeted mutation 2, Mariano Barbacid

Primary Identifier  MGI:2387840 Allele Type  Targeted
Attribute String  Null/knockout Gene  Vav1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Sequences encoding amino acids 135-195 comprising the entire acidic domain were replaced with a PGK-neo cassette via homologous recombination. Gene expression was absent in thymocytes of homozygous mutant animals.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • vav<->,
  • vav<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

19 Publication categories

Trail: Allele