Primary Identifier | MGI:2387675 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Clcn7 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by replacement of exons 3-7 with a neomycin resistance cassette. RT-PCR and Western blot using antibodies directed against the N-terminus of the protein confirmed the absence of gene expression in homozygous mutant mice. |