| Primary Identifier | MGI:2387689 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Thrsp |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacement of a large portion of exon 1 with a PGK-neo cassette. The targeted mutation deletes sequences encoding amino acids 22-150. Northern blot analysis and quantitative RT-PCR was unable to detect gene transcripts from hepatic mRNA of homozygous mutant animals, thus confirming the null allele. |
