| Primary Identifier | MGI:2387691 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Sla |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacement of part of the promoter region and sequences encoding the first 21 amino acids with a neomycin resistance cassette. Northern blot using a probe to the C-terminal region of the gene and RT-PCR analysis of homozygous animals confirmed inactivation of the gene. Sequence analysis of a weak RT-PCR product revealed an alternatively spliced truncated transcript. |
