| Primary Identifier | MGI:2386989 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Ren1 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 1 through 7 were replaced by homologous recombination of a cassette containing GFP and neo. Southern blot analysis confirmed that the targeting vector hybridized exclusively to Ren1 and not to Ren2. RT-PCR analyses of kidney tissue confirmed the absence of endogenous transcript in homozygous mutant mice. Expression of GFP was verified in both heterozygous and homozygous mutant mice. |
