Primary Identifier | MGI:2387091 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Cebpa |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A partial rat Cebpa gene carring a valine to alanine substitution at position 287 (V270A) and a glutamic acid to alanine substitution at position 290 (E290A) in the basic region alpha helix replaced the corresponding portion of the mouse gene via homologous recombination. A neo resistance marker was also introduced downstream of Cepba for positive selection. |