First Author | Sullivan BM | Year | 2013 |
Journal | J Virol | Volume | 87 |
Issue | 7 | Pages | 4071-4 |
PubMed ID | 23325690 | Mgi Jnum | J:197218 |
Mgi Id | MGI:5491127 | Doi | 10.1128/JVI.03268-12 |
Citation | Sullivan BM, et al. (2013) Is the TAM receptor Axl a receptor for lymphocytic choriomeningitis virus?. J Virol 87(7):4071-4 |
abstractText | A recent publication indicated that overexpression of Axl, a cellular receptor that negatively regulates Toll-like receptor signaling, enhanced the entry of viruses pseudotyped with the glycoprotein of lymphocytic choriomeningitis virus (LCMV) in vitro. In testing the biological relevance of these observations, we found differences in neither viral kinetics between LCMV infections of Axl(-/-) and wild-type mice nor T-cell responses prior to spontaneous viral clearance. Thus, Axl is not required for productive LCMV infection of mice. |