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Allele : Smcp<tm1Wen> sperm mitochondria-associated cysteine-rich protein; targeted mutation 1, Wolfgang Engel

Primary Identifier  MGI:2387973 Allele Type  Targeted
Attribute String  Null/knockout Gene  Smcp
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced by a neomycin selection cassette inserted by homologous recombination. Normal transcript was undetected in homozygous mutant mice by Northern blot analysis of testicular RNA. Western blot analysis showed that only the neomycin protein, and not the normal protein, was produced from the disrupted allele.
  • mutations:
  • Disruption caused by insertion of vector
  • synonyms:
  • Smcp<->,
  • Smcp<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele