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Allele : Top3b<tm1Jcw> topoisomerase (DNA) III beta; targeted mutation 1, James C Wang
Primary Identifier  MGI:2388157 Allele Type  Targeted
Attribute String  Null/knockout Gene  Top3b
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A region of the gene spanning nucleotides 777 to 1490 of the coding sequence was replaced with a PGK-neo cassette. This region includes the active site tyrosine 336. Gene expression was undetectable by RT-PCR analysis of liver mRNA from homozygous mutant animals.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • top3beta<-/->,
  • top3beta<-/->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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