Primary Identifier | MGI:2388580 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Pim1-Frat1)5Brn |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A 920 bp fragment encompassing the Frat1 coding region was adjoined to the Pim1 promoter region and 2 immunoglobulin heavy chain enhancers (E-mu). The Frat1 coding region was followed by a Moloney murine leukemia virus (MoMuLV) long terminal repeat. Northern blot analysis detected expression of the the transgene in all tissues tested. This founder line harbored 2 to 3 copies of the transgenic construct. |