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Allele : Oprd1<tm1Jep> opioid receptor, delta 1; targeted mutation 1, John E Pintar

Primary Identifier  MGI:2387891 Allele Type  Targeted
Attribute String  Null/knockout Gene  Oprd1
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced by a neomycin selection cassette inserted by homologous recombination. Protein was undetected in homozygous mutant mice using an antiserum directed against the amino terminal. Furthermore, an absence of ligand binding was determined via autoradiographic analysis of radiolabeled ligands that preferentially bind to the pharmacologically defined receptors, delta1 and delta2.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • DOR-KO,
  • DOR-KO,
  • DOR-1 KO,
  • DOR-1 KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories

Trail: Allele