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Allele : Esr1<tm1.1Lja> estrogen receptor 1 (alpha); targeted mutation 1.1, J Larry Jameson
Primary Identifier  MGI:2388616 Allele Type  Targeted
Gene  Esr1 Transmission  Germline
Strain of Origin  129P2/OlaHsd-Hprt1<b-m3> Is Recombinase  false
Is Wild Type  false
molecularNote  The floxed neo cassette was removed from Esrtm1Lja by in vivo cre mediated recombination. The glutamate to alanine and glycine to alanine missense mutations at codons 207 and 208 were left intact. Expression of mutant transcript and protein was verified by RT-PCR and Western blot analyses of liver tissue.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • ERalpha<AA>,
  • NERKI,
  • ERalpha<NERKI>,
  • NERKI<->,
  • NERKI,
  • ERalpha<AA>,
  • NERKI<->,
  • ERalpha<NERKI>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

31 Publication categories

Trail: Allele




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