| Primary Identifier | MGI:2388628 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Grpr |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 5' portion of exon 2 was deleted by the insertion of a neomycin selection cassette. RT-PCR analysis demonstrated the absence of normal transcript in mutant mice. Functional ablation was demonstrated by monitoring body temperature after the administration of gastrin releasing peptide (Grp). A ligand binding assay further confirmed the absence of functional protein. |
