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Allele : Tg(Lck-Map3k8)3456Ngc transgene insertion 3456, Neal G Copeland
Primary Identifier  MGI:2388710 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Lck-Map3k8)3456Ngc
Strain of Origin  (C57BL/6J x C3H/HeJ)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  A modified Map3k8 cDNA in which viral LTR sequence replaced exon 8 was adjoined to a lck proximal promoter, active in thymocytes. The transgene encodes a truncated protein which lacks the 23 carboxy terminal residues, resembling the truncated protein which is produced after integration of the Moloney murine leukemia virus (MoMLV) at the Map3k8 locus. Expression analysis confirmed the expression of a truncated protein.
  • mutations:
  • Insertion
  • synonyms:
  • Tpl-2tr,
  • Tpl-2tr
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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3 Publication categories

Trail: Allele




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