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Allele : Map3k8<tm1Pnt> mitogen-activated protein kinase kinase kinase 8; targeted mutation 1, Phillip Tsichlis

Primary Identifier  MGI:2388714 Allele Type  Targeted
Attribute String  Null/knockout Gene  Map3k8
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence extending from within exon 3 to within exon 5 was replaced by a neomycin selection cassette. The deleted region encoded a portion of the catalytic domain including ATP binding site and the activation loop. Transcript was detected by Northern blot analysis of homozygous mutant splenocytes.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Tpl2 -,
  • Tpl2 -,
  • Map3k8<tm1Ceci>,
  • Map3k8<tm1Ceci>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

55 Publication categories

Trail: Allele