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Allele : Zap70<tm2.1Mmal> zeta-chain (TCR) associated protein kinase; targeted mutation 2.1, Marie Malissen

Primary Identifier  MGI:2388918 Allele Type  Targeted
Attribute String  Not Specified Gene  Zap70
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An intronic floxed neo cassette was removed by crossing to a cre-expressing deleter strain, leaving behind a tyrosine to phenylalanine knock-in mutation at position 315 (Y315F). Expression of the mutant allele was confirmed by sequence analysis of RT-PCR products from thymus of mutant animals.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • ZAP-70 Y315F,
  • ZAP-70 Y315F
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories