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Allele : Tg(SFTPC-TGFA)1Kor transgene insertion 1, Thomas R Korfhagen

Primary Identifier  MGI:2389218 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(SFTPC-TGFA)1Kor
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
description  This allele is representative of several transgenic founders (H8, H9, G2, E1, 43, and 44). Founders 43 and 44 are smaller compared to age-matched littermates. Founder H9 exhibits ruffled fur and appeared lethargic at time of death.
molecularNote  The entire coding region of human TGFA was fused to the human SFTPC promoter and used for the transgene. Introns from the human growth factor gene were included to enhance transgene expression. The transgene is expressed in lung epithelial cells.
  • mutations:
  • Insertion
  • synonyms:
  • SP-C-TGF-alpha-hGH,
  • SP-C-TGF-alpha-hGH
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele