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Allele : Tnfrsf13c<Bcmd1> tumor necrosis factor receptor superfamily, member 13c; B-cell maturation defect 1

Primary Identifier  MGI:2389403 Allele Type  Spontaneous
Gene  Tnfrsf13c Strain of Origin  A/WySnJ
Is Recombinase  false Is Wild Type  false
molecularNote  In the A/WySnJ strain of mice, an intracisternal type A particle retrotransposon insertion occurred in exon 3, resulting in the replacememt of the final 8 amino acids of the encoded protein with 21 amino acids from the inserted element. This mutation is not present in A/J. FACS analysis indicated that an aberrant fusion protein was expressed from this allele that appeared on the cell surface; however, the protein appeared to be nonfuctional.
  • mutations:
  • Transposon insertion
  • synonyms:
  • Bcmd1<A/WySnJ>,
  • Bcmd1<A/WySnJ>,
  • Baffr<m>,
  • Baffr<m>,
  • Tnfrsf13c<Bcmd1-A/WySnJ>,
  • Tnfrsf13c<Bcmd1-A/WySnJ>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

17 Publication categories

Trail: Allele