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Allele : Socs6<tm1Dlk> suppressor of cytokine signaling 6; targeted mutation 1, Danielle L Krebs

Primary Identifier  MGI:2429394 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Socs6
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  The entire open reading frame was replaced with a cassette containing lacZ and neo inserted at the enodgenous start codon by homologous recombination. Neither transcript nor protein was undetected by Northern or Western blot analyses of a variety of tissues obtained from homozygous mutant mice. Expression of beta-galactosidase was driven by the endogenous promoter.
  • mutations:
  • Disruption caused by insertion of vector
  • synonyms:
  • SOCS-6 -,
  • SOCS-6 -
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele