Primary Identifier | MGI:1857044 | Allele Type | Radiation induced |
Gene | sll1 | Inheritance Mode | Recessive |
Strain of Origin | (C3H/HeH x 101/H)F1 | Is Recombinase | false |
Is Wild Type | false |
description | Using an inversion, In(X)1H, to suppress X Chromosome crossing over, daughters of X-irradiated males were scanned for X Chr lethal mutations. Male offspring of one such die postnatally, within about a day of birth. They appear grossly normal and do suckle (J:13789). |
molecularNote | This mutation was initially identified by its neonatal lethal phenotype in hemizygous male offspring of daughters of X-ray treated male mice in experiments employing the inversion In(X)1H to suppress X Chromosome recombination. It later was found to be associated with a new inversion, designated In(X)3H, whose probable breakpoints are in bands A2 and F1; the phenotype does not segregate from the inversion. |